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A DNA-Based Archival Storage System

TitelA DNA-Based Archival Storage System
PublicatietypeCongres presentatie
Publicatiejaar2016
AuteursBornholt, J., Lopez R., Carmean D. M., Ceze L., Seelig G., & Strauss K.
UItgaveProceedings of the Twenty-First International Conference on Architectural Support for Programming Languages and Operating System
Pagina's637–649
UitgeverACM
Plaats uitgaveNew York, NY, USA
ISBN Nummer978-1-4503-4091-5
RefMan10038
Other NumbersBornholt:2016:DAS:2872362.2872397
Samenvatting

Demand for data storage is growing exponentially, but the capacity of existing storage media is not keeping up. Using DNA to archive data is an attractive possibility because it is extremely dense, with a raw limit of 1 exabyte/mm3 (109 GB/mm3), and long-lasting, with observed half-life of over 500 years. This paper presents an architecture for a DNA-based archival storage system. It is structured as a key-value store, and leverages common biochemical techniques to provide random access. We also propose a new encoding scheme that offers controllable redundancy, trading off reliability for density. We demonstrate feasibility, random access, and robustness of the proposed encoding with wet lab experiments involving 151 kB of synthesized DNA and a 42 kB random-access subset, and simulation experiments of larger sets calibrated to the wet lab experiments. Finally, we highlight trends in biotechnology that indicate the impending practicality of DNA storage for much larger datasets.

URLhttps://homes.cs.washington.edu/~luisceze/publications/dnastorage-asplos16.pdf
DOI10.1145/2872362.2872397
Citation Keyref_10038

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Datum eerste publicatie: 
maandag, 25 april 2016 - 6:30pm
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